Bold running back predictions NFL Week 6: Kenneth Walker, Ashton Jeanty & more

This week’s NFL running back predictions focus on matchups shaped by run defense pressure and pass-game roles. Kenneth Walker III is projected to rush for 200+ yards against the Chargers on Oct. 4, 2026, with the case built on his ability to force missed tackles, generate long runs and benefit from Kansas City’s offensive structure. The piece cites Walker’s 537 yards on 87 carries and notes Los Angeles allows about 3.8 yards per carry. Ashton Jeanty is forecast to catch 10+ passes for 100+ receiving yards against the Bills on Jan. 4, 2026, emphasizing Raiders’ reliance on quick passes and Jeanty’s dual production—22 catches for 215 yards in five games—within a Cousins-led scheme.