Illinois vs. Ohio State odds, prediction: Week 4 college football picks for Saturday - CBS Sports

Ohio State hosts Illinois on Saturday for a Week 4 Big Ten matchup at Ohio Stadium in Columbus, Ohio, with kickoff set for noon ET. The No. 7 Buckeyes (2-1) aim to build on a 59-3 blowout win over Kent State after rebounding from a 24-23 road loss to No. 4 Texas in Week 2. Illinois comes in 2-1 as well, following a 48-10 rout of Southern Illinois after a Week 2 loss to Duke. The latest odds list Ohio State as 27.5-point favorites and total points at 53.5.