Iowa vs. Michigan odds, prediction: Week 4 college football picks for Saturday - CBS Sports

No. 17 Iowa visits No. 18 Michigan in a Big Ten Week 4 matchup with both teams undefeated and leaning on defense. Kickoff is set for 3:30 p.m. ET at Michigan Stadium in Ann Arbor. The SportsLine Projection Model lists Michigan as 5.5-point favorites, with an over/under of 38.5 total points. Michigan (3-0) needed a near-miss vs. Western Michigan in its opener but rebounded with wins over Oklahoma and UTEP, scoring 52 points against UTEP in Week 3. Iowa (3-0) had a 16-13 win over rival Iowa State after two shutdowns. Simulations project the game to land on the Over despite the defenses allowing just 4.3 points (Iowa) and 13.0 (Michigan).