Packers vs Lions Prediction, Pick, Odds for NFL Week 7

The Green Bay Packers (4-2) play the Detroit Lions (3-2) in NFL Week 7 on Sunday, October 25. Kickoff is set for 4:25 p.m. EDT from Ford Field in Detroit, with FOX broadcasting the game. Detroit is favored by -3, and the over/under is 53.5 total points. The Lions sit at -173 on the moneyline, while Green Bay is a +143 underdog (listed as Packers +150 in the odds breakdown). The betting lean presented is the over 53.5, citing Green Bay’s downfield passing efficiency, including 14 completed passes of 30+ yards through six weeks, and Detroit’s struggles defending passing lanes. The Lions have allowed 14 touchdown throws with only three interceptions and rank 31st in air success allowed at 57%.