Who wins in NFL Week 5? Predictions for every game

Week 5 of the NFL schedule features several headline matchups, including AFC and NFC West showdowns. The Seahawks visit the 49ers in a battle of NFC West contenders, while the Rams take on the Bills at SoFi Stadium in what’s framed as a potential Super Bowl preview. The most lopsided-looking slate is Houston Texans vs. Tennessee Titans, both winless, on Oct. 11 on CBS at 1 p.m.—with the article’s prediction leaning heavily toward Houston losing and even jokes about a tie. Other picks include Bengals over Dolphins, Lions over Cardinals, and Falcons over Ravens. Key injured notes include Ja’Marr Chase in concussion protocol and Tee Higgins day-to-day.