New Flexible High-Pressure Knife Advances Endoscopic Surgery
A team of researchers unveils a flexible high‑pressure injection knife designed for endoscopic submucosal dissection (ESD), aiming to improve precision, safety, and efficiency in removing early gastrointestinal tumors. The device integrates a high‑pressure fluid injector directly into a highly maneuverable cutting tool, enabling better submucosal lifting and safer separation from the muscularis propria. Preclinical testing in animal models confirmed durable high‑pressure delivery without compromising flexibility, signaling readiness for human trials. In clinical evaluation, patients with early‑stage neoplasms treated with the device showed easier handling and shorter procedure times, with fewer adverse events than conventional ESD instruments.






