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Patriots vs. Bills Week 4 predictions, odds and best bets: Can short-handed New England bounce back in Buffalo?

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Patriots vs. Bills Week 4 predictions, odds and best bets: Can short-handed New England bounce back in Buffalo?
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The New England Patriots (1-2) head to undefeated Buffalo Bills (3-0) at Highmark Stadium on Sunday, Oct. 4 (1:00 PM ET, CBS) for the team’s first AFC East game of the season after a 35-6 loss to Jacksonville. New England will be short-handed: cornerback Christian Gonzalez and defensive tackle Christian Barmore are ruled out with shoulder injuries, and neither practiced this week. Mike Vrabel said there’s “nothing we can do” about the situation. Drake Maye practiced fully despite a throwing-shoulder issue. DraftKings pricing versus machine-learning simulations projects a Patriots win probability of 28.5% and shows the +7 spread as the strongest Patriots betting angle.

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