NFL spread, straight-up picks: Rams, Chiefs, Colts top Week 6 confidence rankings

Week 6 NFL confidence picks lean heavily on a bounce-back slate plus updated injury information, with four teams on bye: Minnesota, Detroit, Cincinnati, and Miami. The Rams are favored both straight-up and against the spread in Cardinals at Rams, listed at Rams -12.5 with a confidence level of 6. The column frames Los Angeles as “back” after a 2-3 start following a Monday night loss to the Bills, pointing to special teams as a recurring issue under Sean McVay. It also highlights offensive names to watch, including Matthew Stafford, Puka Nacua, and Davante Adams. The piece then turns to Chargers at Chiefs as the next item.